On Perma Death, maybe... it isn't a thing for any of the characters in the game...?
So look, there is the TPCD. Do they schedule disasters, so that civilian casualties and destruction of urban area are kept to a minimum? Even at the start of things when we 'see' it for the first time (recap'd by Largo) they don't seem to be doing a very good job at that. I mean, insane respawn powers and insane rebuilding capabilities are one thing, but in any country, such a disaster area as portrayed even there (during the Beer Garden Pushout) would clearly be cordoned off by outside-of-police-force for a lot longer than until evening, even after rebuild is completed. Rebuilding in real life can be fast, but only starts when rubble is cleared AFTER (most of) the bodies are found. Here rebuilding started straight away, ergo - no bodies?
Also during the Megagamers siege by fans of Erika, there were NPC casualties (hey, my head hurts - cause you've glass in your head) and the RR was... measly. Even the Zilla did not die from a head-on impact from the plasma cannon. But Inspector Sonoda, he was sitting on its head - and then, he's on the ground unscathed all of a sudden.
Or the not-shiny impact on the NPC beside Megumi. The Horde started respawning in place almost straight away and Megumi respawned a few tens of meters away. tattered and distraught at what she thought Kimiko's death was, but otherwise, pretty intact.
Even Piro... after giving his train card to Kimiko... when walking over the train line - was he only close to jumping off the bridge, or he really DID, and respawned back on the bridge straight away? Largo's electric shock resistance now makes much more sense. And the insane healing (being bumped into forehead like Piro was, would clearly leave a mark... not a mark on him; Kimiko's invisible broken nose; Largo's being able to stand up from the wheelchair and launch anti-tank missiles not long after arriving to the scene and not THAT long after having m3d wobblez, that had him use the wheelchair in the first place...).
The muffin cart driver after being hit by a pole - I mean his cabin was smack bang in the middle of the crumple zone, he could not have survived if this was normal physics environment. But there he is on the pavement lamenting the state of his scooter instead.
Miho's heart surgery, she's up no more than 12h after? OK i know keyhole surgery exists and all, and it's probably less blood loss than from a broken nose... she may feel weak and not have all her powers back, but still the recovery rate is insane.
So i think in this game, NPC or not, you can not /really/ die from physical injuries. I mean it's a game, and a comic, normal physics don't apply to bodies (maybe apart from Yutaka, but he's healing his ribs, arms and internal organs also insanely fast - he may be bandaged stiff now but he's able to stand already!).
Yuki may have fallen off the wires on top of Yutaka, but this is still something - with normal humans, both would die from such impact (there are rl examples of window jumpers dying and taking random individuals below with them...). While the magical girl did not even suffer a bruise, Chewtoy 'only' landed in hospital. But maybe they actually did die, and respawned in place, and Yutaka's injuries come from being too close to Yuki's spawn point... or he really respawned on the road straight in the face of a dark blue sedan...?
The difference between other players, NPC's and Miho may be that - they don't remember or don't feel their Deaths as a particularly painful experience. Injuries are more painful than death is. It's something that happens, and then you're continuing after respawn. Not so for Miho - to her, dying hurts. Even if the heart surgery hurts more, 'more than it used to'.
Is she playing by Neuralink ?

while everybody else plays with game controllers or keyboards ?
